Change in heart rate variability in relation to a significant ST-event associates with newborn metabolic acidosis.

نویسندگان

  • S Siira
  • T Ojala
  • E Ekholm
  • T Vahlberg
  • S Blad
  • K G Rosén
چکیده

OBJECTIVE To find whether low-to-high frequency (LF/HF) ratio of fetal heart rate (FHR) variability changes in relation to a significant ST-event during delivery, and if the change is predictive of metabolic acidosis of the newborn. DESIGN A case-control study. SETTING Data from a multicentre project. SUBJECTS Acidotic and control fetuses with abnormal cardiotocography together with a ST-event in fetal electrocardiogram (ECG). METHODS We studied intrapartum FHR variability with spectral analysis from 34 fetuses with a significant ST-event in the fetal ECG. LF/HF ratio of FHR variability was measured within a period of 1 hour before and 1 hour after a significant ST-event. Sensitivity and specificity of the change in LF/HF ratio of FHR variability in prediction of metabolic acidosis (pH < or = 7.05 and base deficit value > 12.0 mmol/l) of the newborn were described by means of the receiver operating characteristic curve. MAIN OUTCOME MEASURES Change in LF/HF ratio of FHR in relation to a significant ST-event. RESULTS We found that a relative change in LF/HF ratio greater than 30% in relation to a significant ST-event predicted cord arterial metabolic acidosis with a sensitivity of 89% (95% CI 68-100%) and specificity of 80% (95% CI 64-96%). CONCLUSIONS Relative changes in LF/HF ratio of FHR variability in relation to a significant ST-event are more pronounced in fetuses born with metabolic acidosis.

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عنوان ژورنال:
  • BJOG : an international journal of obstetrics and gynaecology

دوره 114 7  شماره 

صفحات  -

تاریخ انتشار 2007